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Azlocillin Sodium 1 g

Price:
$80.00
SKU:
TE-A023-1G
Quantity:

Azlocillin Sodium

Purity > 90.0%

  CAS Number:
  37091-65-9
  Chemical Formula:
  C20H22N5NaO6S
  Molecular Weight:
  483.47 g/mol

 

Azlocillin is a semi-synthetic antibiotic derived from ampicillin and possesses a broader spectrum than carboxy penicillins. It has a strong in vitro potency and works by inhibiting the last stages of cell membrane construction.

β-Lactam antibiotics work by breaking up the peptidoglycan links in cell walls of non-resistant bacteria and triggers the release of hydrolases and autolysins which further break down the cell wall. In contrast to most cephalosporins, Azolocillin exhibits activity against enterococci.

Azlocillin functions by inhibiting the formation of peptidoglycan cross-links in the bacterial cell wall. The β-lactam moiety (functional group) of penicillin binds to the enzyme (DD-transpeptidase) that links the peptidoglycan molecules in bacteria, which weakens the cell wall of the bacterium. In addition, the build-up of peptidoglycan precursors triggers the activation of bacterial cell wall hydrolases and autolysins, which further digest the bacteria's existing peptidoglycan.

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Celebrity Endorsements

Guzmán, Flavio, MD. "Beta Lactams Antibiotics (penicillins and Cephalosporins) Mechanism of Action.” Medical Pharmacology. Pharmacology Corner, 29 Nov. 2008.

Pitout JD, Sanders CC, Sanders WE Jr. Antimicrobial resistance with focus on beta-lactam resistance in gram-negative bacilli. Am J Med 1997; 103:51.

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